My research interests lie in the field of genetic epidemiology, focusing on genetic and environmental risk factors for cardiovascular and metabolic traits and diseases. I have a particular interest in the concept of “Developmental Origins of Health and Disease”, i.e. the impact of the early environment on cardiometabolic risk factors in adulthood. Additionally, I am studying the contribution of parent-of-origin effects to adult cardiometabolic health, examining both genomic imprinting and maternal genotype effects on the intrauterine environment.
Dior UP, Hochner H*, Friedlander Y, Calderon-Margalit R, Jaffe D, Burger A, Avgil M, Manor O, Elchalal U. Association between number of children and mortality of mothers: results of a 37-year follow-up study. Ann Epidemiol, 2013. 23(1):13-8.
Lin D, Weinberg CR, Feng R, Hochner H, Chen J. A Multi-Locus Likelihood Method for Assessing Parent-Of-Origin Effects Using Case-Control Mother-Child Pairs. Genetic Epidemiology 2012. Genet Epidemiol, 2012. doi: 10.1002/gepi.21700.
Hochner, H, Friedlander Y, Calderon-Margalit R, Meiner V, Sagy Y, Avgil-Tsadok M, Burger A, Savitsky B, Siscovick DS, and Manor O. Associations of maternal prepregnancy body mass index and gestational weight gain with adult offspring cardiometabolic risk factors: the Jerusalem Perinatal Family Follow-up Study. Circulation, 2012. 125(11): p. 1381-9. Published with editorial: Gillman MW. Gestational Weight Gain: Now and the Future. Circulation, 2012. 125(11): p. 1339-40.
Chen J, Lin D, Hochner H. Semiparametric maximum likelihood methods for analyzing genetic and environmental effects with Case-Control mother-child pair data. Biometrics, 2012. 68(3):p. 869-77.
Tsadok MA, Friedlander Y, Paltiel O, Manor O, Meiner V, Hochner H, Sagy Y, Sharon N, Yazdgerdi S, Siscovick D, Elchalal U. Obesity and blood pressure in 17-year-old offspring of mothers with gestational diabetes: insights from the Jerusalem Perinatal Study. Exp Diabetes Res 2011;2011:906154.
Friedlander Y, Manor O, Paltiel O, Meiner V, Sharon N, Calderon R, Hochner H, Sagy Y, Avgil M, Harlap S, Siscovick DS. Birth Weight of Offspring, Maternal Pre-pregnancy Characteristics, and Mortality of Mothers: The Jerusalem Perinatal Study Cohort. Ann Epidemiol 2009;19(2):112-7.
Weiss-Salz I, Harlap S, Friedlander Y, Kaduri L, Levy-Lahad E, Yanetz R, Deutsch L, Hochner H, Paltiel O. Ethnic ancestry and increased paternal age are risk factors for breast cancer before the age of 40 years. Eur J Cancer Prev 2007;16(6):549-54.
Paltiel O, Friedlander Y, Deutsch L, Yanetz R, Calderon-Margalit R, Tiram E, Hochner H, Barchana M, Harlap S, Manor O. The interval between cancer diagnosis among mothers and offspring in a population-based cohort. Fam Cancer 2007;6(1):121-9.