• Neurodegenerative disorders
• Prion diseases
• Creutzfeldt-Jakob disease (CJD)
The molecular genetics and biochemistry of CJD in Libyan Jews
Research in this subject includes following the mutation that causes the disease in families, looking for explanations for partial penetrance and studying the structure of the mutant protein in patients and mutation carriers.
The association between the prion protein and heparin
We study the biochemistry of the binding between PrP and heparin, and the changes caused by heparin molecules of different molecular weights on the properties of prion proteins.