N. Debotton, M. Parnes, J. Kadouche and S. Benita, Overcoming the formulation obstacles towards targeted chemotherapy: in vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles. J. Control. Rel.,127, pp 219-230 (2008)
T. Hagigit, T. Nassar, F. Behar-Cohen, G. Lambert and S Benita, The influence of cationic lipid type on in-vitro release kinetic profiles of antisense oligonucleotide from cationic nanoemulsions. Eur. J. Pharm. Biopharm., 70, pp 248-259 (2008)
T. Nassar, A. Rom, A. Niska and S. Benita, A novel nanocapsule delivery system to overcome intestinal degradation and drug transport limited absorption of P-glycoprotein substrate drugs. Pharm. Res., 25, pp 2019-2029 (2008)
O. Harush-Frenkel, Y. Altschuler and S. Benita, Nanoparticle-cell interactions-drug delivery implications. Critical Reviews in Therapeutic Drug Carrier Systems, 25, pp 485-544 (2008)
T. Nassar, A. Rom, A. Niska and S. Benita, Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of Tacrolimus, a P-gp substrate drug. J. Control. Rel., 133, pp 77-84 (2009)
D. Goldstein and S. Benita, Paclitaxel-palmitate loaded anti-HER2 cationic immunoemulsion: pharmacokinetic and biodistribution study in healthy mice. J. Drug Del. Sci. Technol.,19, pp 269-275 (2009)
N. Debotton, O. Giladi, M. Parnes and S. Benita, Novel high content paclitaxel palmitate nanospheres for improved cancer treatment. J. Drug Del. Sci. Technol., 19, pp 275-282 (2009)
N. Debotton, H. Zer, M. Parnes, O. Harush-Frenkel, J. Kadouche and S.Benita, A quantitative evaluation of the molecular binding affinity between a monoclonal antibody conjugated to a nanoparticle and an antigen by surface plasmon resonance., Eur. J. Pharm. Biopharm., 74, pp 148-56 (2010)
T. Hagigit, M. Abdulrazik, F. Orucov, F. Valamanesh, M. Hagedorn, G. Lambert, F. Behar-Cohen and S. Benita, Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye. J. Control. Rel., 145, pp 297-305 (2010)
O. Harush-Frenkel, M. Bivas Benita, T. Nassar, C. Springer, Y. Sherman, A. Avital, Y. Altschuler, J. Borlak and S. Benita, A safety and tolerability study of differently charged nanoparticles for local pulmonary drug delivery. Toxicology and Applied Pharmacology, 246, pp 83-90 (2010)
T. Nassar, SA. Qadri, OH. Frenkel, S. Farber, S. Lecht, P. Lazarovici, and S. Benita, High plasma levels and effective lymphatic uptake of docetaxel in an orally-available nanotransporter formulation. Cancer Res., 71, pp 3018-28 (2011)
N. Karra and S. Benita, The ligand nanoparticle conjugation approach for targeted cancer therapy., Curr. Drug Metab., (2011), In Press
T. Hagigit, M. Abdulrazik, F. Valamanesh, F. Behar-Cohen and S. Benita, Ocular antisense oligonucleotide delivery by cationic nanoemulsion for improved treatment of ocular neovascularization: An in-vivo study in rats and mice. J. Control. Rel., (2011), In Press
F. Lallemand, P. Daull, S. Benita, R. Buggage and J.-S. Garrigue, Successfully improving ocular drug delivery using the cationic nanoemulsion, Novasorb. Journal of Drug Delivery, Received 2011, Volume 2012, In Press
G. Cohen, S. Lecht, H. Arien-Zakay, K. Ettinger, O. Amsalem, M. Oron-Herman, E. Yavin, D. Prus, S. Benita, A. Nissan and P. Lazarovici, Bio-imaging of Colorectal Cancer Models Using Near Infrared Labeled Epidermal Growth Factor. PLoS One, 2012;7(11):e48803. doi: 10.1371/journal.pone.0048803. Epub 2012 Nov 8.
N. Karra, T. Nassar, F. Laenger, S. Benita* and J. Borlak*. Safety and Proof-of-Concept Efficacy of Inhaled Drug Loaded Nano- and Immunonanoparticles in a c-Raf Transgenic Lung Cancer Model. Curr. Cancer Drug Targets, 13, pp11-29 (2013).
N. Karra, T. Nassar, A. Nemirovski Ripin, O. Schwob, J. Borlak and S. Benita. Antibody Conjugated PLGA Nanoparticles for Targeted Delivery of Paclitaxel Palmitate: Efficacy and Biofate in a Lung Cancer Mouse Model. Small, 2013. DOI 10.1002/smll.201301417.
S. Attili-Qadri, N. Karra, A. Nemirovski, O. Schwob , Y. Talmon, T. Nassar, S. Benita. Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption. Proc. Natl. Acad. Sci. USA. 2013 Oct 22;110(43):17498-503. Doi 10.1073/pnas. 1313839110. Epub 2013 Oct 7
A. Badihi A, N. Debotton, M. Frušić-Zlotkin, Y.Soroka, R Neuman,S. Benita. Enhanced cutaneous bioavailability of dehydroepiandrosterone mediated by nano-encapsulation. J Control Release. 2014 Sep 10;189:65-71.
L.Soudry-Kochavi, N. Naraykin, T. Nassar T, S. Benita. Improved oral absorption of exanatide using an original nanoencapsulation and microencapsulation approach. J Control Release. 2015 Nov 10;217:202-10