Research Hub: Epigenetics
Coordinators: PhD candidate Fernando Castellani and Dr. Maayan Salton
The Hebrew University Faculty of Medicine may accurately be called the international home of epigenetics. It was here that this field was founded, and that the basic rules of epigenetic gene regulation were established. Today, scientists at IMRIC continue to be the pioneers of this field, initiating new research directions in the ongoing effort to understand the epigenetic code and its implications for health and disease.
The purpose of this hub is to bring together scientists and physicians working in the fields of epigenetics and nuclear architecture in health and disease. Epigenetic programming patterns are responsible for the most basic aspects of biology, and they are as well greatly involved in disease biology and healing. Deciphering this code thus represents a promising route for better diagnosis, treatment and prevention of various diseases.
Covering the entire span of human life from epigenetics in embryology to aging; DNA methylation to DNA repair; mRNA regulation to immunology; individual-to-inheritance-to-populations; in health, disease, cancer and diabetes; in treatment, development, and epigenetic memory; IMRIC aims to create a well-rounded community of scientists, pushing forwards the boundaries of the epigenetic field. The group seminars and lectures organized by this hub aim to encourage collaborative work, to challenge a new generation of researchers to excellence, to empower inspirational work, to connect new and experienced members, and to equip for success.
Current hub members:
Prof. Yehudit Bergman: Stem cell biology; molecular biology of lymphomas and leukemias; DNA methylation.
Prof. Howard Cedar: DNA methylation and chromatin structure, major effectors in all forms of cancer.
Prof. Yuval Dor: Epigenetic liquid biopsies.
Dr. Rachel Eiges: Epigenetics of unstable repeat pathologies, and pluripotent stem cells.
Prof. Asaf Hellman: Epigenetics of populations.
Dr. Maayan Salton: Epigenetic regulation of alternative splicing.
Prof. Itamar Simon: Epigenetics effects on mutation rates and distribution in cancer and normal tissues.
Prof. Rami Aqeilan: DNA breaks and chromatin structure.
Dr. Sheera Adar: DNA damage and repair and their consequences on transcription and mutagenesis.
Dr. Yotam Drier: Epigenomics and chromosome topology of cancer and genetic diseases.
Prof. Yossi Buganim: Epigenetics of stem cell biology, reprogramming, and cell fate decisions.
We are accepting new members.
Next meeting:
March 27th 2024 10:00 - 14:00
Previous hub meetings:
May 17th 2016 8:30 - 13:00 Seligman Hall, Faculty of Medicine
June 22nd 2016 8:30 - 12:30, Botnar Auditorium, IMRIC
January 19th 2017 8:30 - 12:15 Lecture Hall Daled, Faculty of Medicine
April 26th 8:30 2017 - 12:00 Seligman Hall, Faculty of Medicine
June14th 8:30 2017 - 12:00 Faculty Club, Faculty of Medicine
