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Last Publications

Benita, Simon

Nassar Taher, Rohald Ayala, Naraykin Natalya et al., Nanocapsules embedded in microparticles for enhanced oral bioavailability and efficacy of Lopinavir as an anti-AIDS drug, Journal of Drug Targeting Volume: 27, Issue: 5-6, Special Issue: SI, Pages: 590-600, Jul 3 2019
Soudry-Kochavi Liat, Naraykin Natalya, Di Paola Rosanna et al., Pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro-resistant microparticles European, Journal of Pharmaceutics and Biopharmaceutics, Volume: 133, Pages: 214-223, Dec 2018
Abd Elrahman Ihab, Nassar Taher, Khairi Noha et al., Minit-Livin Conjugated to Targeted Nanoparticles Inhibits Tumorigenicity, Blood Volume: 132 Supplement: 1 Meeting Abstract: 4171 Nov 29 2018

Benny, Ofra

Amoyav B, Benny O.Microfluidic Based Fabrication and Characterization of Highly Porous Polymeric Microspheres. Polymers (Basel). 2019 Mar 5;11(3). pii: E419. doi: 10.3390/polym11030419.
Karsch-Bluman A, Feiglin A, Arbib E, Stern T, Shoval H, Schwob O, Berger M, Benny O. Tissue necrosis and its role in cancer progression.Oncogene. 2019 Mar;38(11):1920-1935. doi: 10.1038/s41388-018-0555-y. Epub 2018 Nov 2.
Arnon Fluksman, Ofra Benny. A robust method for critical micelle concentration determination using coumarin-6 as a fluorescent probe. Analytical methods, published on 01 Jul 2019
Eva Abramov, Ouri Schwob, Ofra Benny. Film- and ointment-based delivery systems for the transdermal delivery of TNP-470. Polymers advanced technologies, First published: 18 June 2019

Bialer, Meir

Bialer M., Johannessen S.J., Koepp M., Levy R.H., Perucca E., Tomson T., White H. S. Progress report on new antiepileptic drugs: A summary of the fourteen Eilat Conference on new antiepileptic drugs and devices (EILAT XIV).I. Drugs in preclinical and early clinical development. Epilepsia 59: 1811-1841 (2018).
Ying L.L, Bialer M, Cabrera R.M, Finnell R.H, Wlodarczyk B. J. Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice. Birth Def. Res.92: 1-11 (2018).
Haine K. M., Matson L. M., Dunn E. N., Ardinger C E., Bibi D., McDonough J. H., Bialer M. Comparative efficacy of valnoctamide and sec-butylpropylacetamide (SPD) in terminating nerve Agents-Induced seizures in pediatric rats. Epilepsia 60: 315-321 (2019).
Bialer M., Johannessen S.J., Levy R.H., Perucca E., Tomson T., Koepp M.J., White H. S. Virtual special issue “Neuromodulation”: A summary of the data presented at the XIV conference on new antiepileptic and devices (EILAT XIV). Epilepsy Res. 153:66-67 (2019).
Bibi D., Shusterman B., Nocentini A., Supuran C. T., Bialer M. Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulfamoylphenyl carbamate derivative. J. Enzyme Inhibit. Med. Chem, 34:1078-1082 (2019).

Blum, Galia

Meena Naresh, Pattanayak Shakti, Ben-Nun Yael, Benhamron SandrineT, Kumar SaranS Merquiol EmmanuelleT; Hoevelmeyer NadineS, Blum Galia*PI and Tirosh Boaz*PI. mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity. Immunology, 155(4):505-518, * Corresponding Author 2018
Tsvirkun DaryaS; Ben-Nun YaelS; Merquiol EmmanuelleT; Zlotver IvanS; Meir KarenC; Weiss Sadan TommyS; Matok IlanC; Popovtzer RachelaC; Blum, GaliaPI. CT Imaging of Enzymatic Activity in Cancer using Covalent Probes Reveal a Size-Dependent Pattern. Journal of the American Chemical Society, 140(38):120010-12020 2018
Tommy Weiss-SadanS; Gal ItzhakS, Farnusch KaschaniT, Zhanru YuS, Mohamed MahameedS, Adi AnakiS, Yael Ben-NunS, Emmanuelle MerquiolT, Boaz TiroshC, Benedikt KesslerC, Markus KaiserC and Galia BlumPI. Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation. Molecular and cellular Proteomics, 18(7):1330-1344. 2019
Tommy Weiss-SadanS, Yael Ben-NunS, David MaimounS, Emmanuelle MerquiolT, Ihab Abd-ElrahmanC, Israel GotsmanPI and Galia BlumPI. A Theranostic Cathepsin Activity-Based Probe for Noninvasive Intervention in Cardiovascular Diseases. Theranostics, 2019
Tommy Weiss-SadanS, David MaimounS, Diana OelschlagelS, Farnusch KaschaniT, Danny MisiakS, Hanmant GaikwadS, Yael Ben-NunS, Emmanuelle MerquiolT, Adi AnakiS, Darya TsvirkunS, Markus KaiserC, Patrick MichlC, Israel GotsmanPI and Galia BlumPI. Cathepsins Drive Anti Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells. Cellular Physiology and Biochemistry, 2019

Domb, Avi

Zada, Moran Haim; Kubek, Michael; Khan, Wahid; et al. Dispersible hydrolytically sensitive nanoparticles for nasal delivery of thyrotropin releasing hormone (TRH) Journal of Controlled Release Volume: 295 Pages: 278-289 Feb 2019
Rathi, Sneha; Saka, Raju; Domb, Abraham J.; et al. Protein-based bioadhesives and bioglues Polymers for Advanced Technologies Volume: 30 Issue: 2 Pages: 217-34 Published: Feb 2019
Bulbake, Upendra; Singh, Alka; Domb, Abraham J.; et al. Therapeutic Macromolecular Iron Chelators Current Medicinal Chemistry Volume: 26 Issue: 2 Pages: 323-334 2019
Steinman, Noam Y.; Haim-Zada, Moran; Goldstein, Isaac A.; et al. Effect of PLGA block molecular weight on gelling temperature of PLGA-PEG-PLGA thermoresponsive copolymers Journal of Polymer Science Part A-Polymer Chemistry Volume: 57 Issue: 1 Pages: 35-39 Jan 1 2019
Khan, Wahid; Abtew, Ester; Modani, Sheela; et al. Polysaccharide Based Nanoparticles israel Journal of Chemistry Volume: 58 Issue: 12 Special Issue: SI Pages: 1315-1329 DEC 2018
Brucks, Spencer D.; Steinman, Noam Y.; Starr, Rachel L.; et al. Crosslinked colloids with cyclopropenium cations Journal of Polymer Science Part A-Polymer Chemistry Volume: 56 Issue: 23 Pages: 2641-2645 DEC 1 2018
Basu, Arijit; Domb, Abraham J. Recent Advances in Polyanhydride Based Biomaterials Advanced Materials Volume: 30 Issue: 41 Special Issue: SI Article Number: 1706815 OCT 11 2018
Abedini, Fatemeh; Ebrahimi, Mohammad; Roozbehani, Abbas Hemmati; et al. Overview on natural hydrophilic polysaccharide polymers in drug delivery Polymers for Advanced TechnologieS Volume: 29 Issue: 10 Pages: 2564-2573 OCT 2018
Shadmon, Hodaya; Basu, Arijit; Eckhard, Lea H.; et al. Synthesis, characterization and antibacterial activity of heterocyclic quaternary ammonium polymers New Journal of Chemistry Volume: 42 Issue: 18 Pages: 15427-15435 SEP 21 2018
Kommineni, Nagavendra; Saka, Raju; Khan, Wahid; et al. Non-polymer drug-eluting coronary stents Drug Delivery and Translational Research Volume: 8 Issue: 4 Special Issue: SI Pages: 903-917 AUG 2018
Itin, Constantin; Domb, Abraham J.; Hoffman, Amnon A meta-opinion: cannabinoids delivered to oral mucosa by a spray for systemic absorption are rather ingested into gastro-intestinal tract: the influences of fed / fasting states Expert Opinion on Drug Delivery Aug 2019
Abtew, Ester; Ezra, Aviva F.; Basu, Arijit; et al. Biodegradable Poly(Acetonide Gluconic Acid) for Controlled Drug Delivery Biomacromolecules Volume: 20 Issue: 8 Pages: 2934-2941 Aug 2019
Kasem, Haytam; Shriki, Harel; Ganon, Lihi; et al. Rubber plunger surface texturing for friction reduction in medical syringes friction Volume: 7 Issue: 4 Pages: 351-358 Aug 2019
Daifa, Mahran; Shmoeli, Eliyahu; Domb, Abraham J. Enhanced flocculation activity of polyacrylamide-based flocculant for purification of industrial wastewater Polymers for Advanced Technologies July 2019
SreeHarsha, Nagaraja; Hiremath, Jagadeesh G.; Aitha, Rajesh Kumar; et al. Paclitaxel loaded poly (DL lactic acid co castor oil) 60:40 with poloxamer-F68 rod shape cylindrical nanoparticle preparation and in vitro cytotoxicity studies Polymers for Advanced Technologies Jul 2019
Hosseinkhani, Hossein; Domb, Abraham J. Biodegradable polymers in gene-silencing technology Polymers for Advanced Technologies Jul 2019
Kompella, Uday B.; Domb, Abraham; Urtti, Arto; et al. Ocular Drug Delivery: Nanotechnology, Physical and Chemical Methods, Vitreous Drug Binding, and Aging Eye Journal of Ocular Pharmacology and Therapeutics Jun 2019
Steinman, Noam Y.; Starr, Rachel L.; Brucks, Spencer D.; et al. Cyclopropenium-Based Biodegradable Polymers Macromolecules Volume: 52 Issue: 9 Pages: 3543-3550 May 14 2019
Kommineni, Nagavendra; Mahira, Shaheen; Domb, Abraham J.; et al. Cabazitaxel-Loaded Nanocarriers for Cancer Therapy with Reduced Side Effects Pharmaceutics Volume: 11 Issue: 3 Article Number: 141 Mar 2019
Shapira-Furman, Tovi; Serra, Riccardo; Gorelick, Noah; et al. Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer Journal of Controlled Release Volume: 295 Pages: 93-101 Feb 2019

Eyal, Sara

Han H, Eyal S, Portnoy E, Mann A, Shmuel M, Benifla M, Ekstein D, Polyak B. Monocytes as Carriers of Magnetic Nanoparticles for Tracking Inflammation in the Epileptic Rat Brain. Curr Drug Deliv. 2019 Jun 19. doi: 10.2174/1567201816666190619122456. [Epub ahead of print] PMID: 31237208
Berman E, Eyal S. Drug Interactions in Space: a Cause for Concern? Pharm Res. 2019 May 31;36(8):114. doi: 10.1007/s11095-019-2649-9.
Tetro N, Imbar T, Wohl D, Eisenberg I, Yagel S, Shmuel M, Eyal S. The effects of valproic acid on early pregnancy human placentas: Pilot ex vivo analysis in cultured placental villi. Epilepsia. 2019 May;60(5):e47-e51. doi: 10.1111/epi.14721. Epub 2019 Apr 13.
Granit A, Tetro N, Shmuel M, Peretz T, Eyal S. Lacosamide at therapeutic concentrations induces histone hyperacetylation in vitro. Epilepsia Open. 2018 Oct 30;3(4):535-539. doi: 10.1002/epi4.12269. eCollection 2018 Dec.
Jabareen A, Leker RR, Eyal S, Ekstein D. Treatment with antiepileptic drugs in patients with stroke. A change in clinical practice may be required. J Neurol Sci. 2018 Dec 15;395:4-7. doi: 10.1016/j.jns.2018.09.026. Epub 2018 Sep 22.
Eyal S. The Fever Tree: from Malaria to Neurological Diseases. Toxins (Basel). 2018 Nov 23;10(12). pii: E491. doi: 10.3390/toxins10120491. Review.

Gibson, Dan

Babak, Maria V.; Zhi, Yang; Czarny, Bertrand; et al. Dual-Targeting Dual-Action Platinum(IV) Platform for Enhanced Anticancer Activity and Reduced Nephrotoxicity Angewandte Chemie-International Edition Volume: 58 Issue: 24 Pages: 8109-8114 Published: JUN 11 2019
Kostrhunova, Hana; Petruzzella, Emanuele; Gibson, Dan; et al. An Anticancer Pt-IV Prodrug That Acts by Mechanisms Involving DNA Damage and Different Epigenetic Effects Chemistry-A European Journal Volume: 25 Issue: 20 Pages: 5235-5245 Published: APR 5 2019
Gibson, Dan Multi-action Pt(IV) anticancer agents; do we understand how they work? Journal of Inorganic Biochemistry Volume: 191 Pages: 77-84 Published: FEB 2019

Goldblum, Amiram

Da'adoosh, Benny; Marcus, David; Rayan, Anwar; et al. Discovering highly selective and diverse PPAR-delta agonists by ligand based machine learning and structural modeling Scientific Reports Volume: 9 Article Number: 1106 Jan 31 2019

Golomb, Gershon

Ben David-Naim M., Dagan A., Grad E., Aizik G., Nordling-David M.M., Morss Clyne A., Granot Z., and Golomb G. Targeted siRNA nanoparticles for mammary carcinoma therapy. Cancers, 11(4), 442 (2019). DOI: https://doi.org/10.3390/cancers11040442.
Grad E., Gutman D., Golomb M., Efraim R., Oppenheim A., Richter I., Danenberg H.D. and Golomb G. Monocyte modulation by liposomal alendronate improves cardiac healing in a rat model of myocardial infarction, Regen. Eng. Transl. Med., (2019); https://doi.org/10.1007/s40883-019-00103-8 .
Golomb G., Aizik G. Liposomal formulation comprising bromine-richorganobromines and uses thereof. US Patent application 62/767,569 (2018)
G. Aizik, E. Grad and G. Golomb, Monocyte-mediated drug delivery systems for the treatment of cardiovascular diseases, Drug Deliv. Transl. Res., 8(4), 868-882 (2018)
M. Chorny, R.J. Levy and G. Golomb, Cardiovascular delivery of drugs and biotherapeutics, Drug Deliv. Transl. Res. 8(4), 865-867 (2018)
E. Grad, K. Zolotarevsky, H.D. Danenberg, M.M. Nordling-David, D. Gutman and G. Golomb, The role of monocyte subpopulations in vascular injury following partial and transient depletion, Drug Deliv. Transl. Res., 8(4), 945-953 (2018)
M.M. Nordling-David, E. Rachamin, E. Grad, and G. Golomb, Lysozyme transport to the brain by Liposomes, Prec. Nanomed., 1(2):146-161 (2018). DOI:10.29016/180731.1
G. Aizik, N. Waiskopf, M. Agbaria, M. Ben David-Naim Y. Levi-Kalisman, A. Shahar, U. Banin and G. Golomb, Liposomes of quantum dots configured for passive and active delivery to tumor tissue. Nano Lett. (in press); DOI: 10.1021/acs.nanolett.9b01027

Gorinstein, Shela

Ku, YG., Bae, JH., Namiesnik, J., Barasch, D., Nemirovski, A., Katrich, E., Gorinstein, S. Detection of Bioactive Compounds in Organically and Conventionally Grown Asparagus Spears, Food Analytical Methods, 2018
Ku, YG., Kang, DH., Lee, CK., Lee, SY., Ryu, CS., Kim, DE., Polovka, M., Namiesnik, J., Gorinstein, S. Influence of different cultivation systems on bioactivity of asparagus. 2018, Food Chemistry, 244, 349-358
Lubinska-Szczygiel, M., Rozanska, A., Namiesnik, J., Dymerski, T., Shafreen, RB Weisz, M., Ezra, A., Gorinstein, S. Quality of limes juices based on the aroma and antioxidant properties. 2018. Food Control, 89, 270-279
Lubinska-Szczygel, M., Rozanska, A., Dymerski, T., Namiesnik, J., Katrich, E., Gorinstein, S. A novel analytical approach in the assessment of unprocessed Kaffir lime peel and pulp as potential raw materials for cosmetic applications. 2018, Industrial Crops and Products, 120, 313-321
Somrat, N., Sawadeemit, C., Vearasilp, S., Thanapornpoonpong, SN, Gorinstein, S. Effects of different binder types and concentrations on physical and antioxidant properties of pelleted sweet corn seeds. 2018, European Food Research and Technology, 244, 547-554
Maulidiani, M., Mediani, A., Abas, F., Park, YS., Park, YK., Kim, YM., Gorinstein, S. 1H NMR and antioxidant profiles of polar and non-polar extracts of persimmon (Diospyros kaki L) - metabolomics study based on cultivars and origins. 2018, Talanta, 184, 277-286
Shafreen, RB., Lubinska-Szczygel, M., Rozanska, A., Dymerski, T., Namiesnik, J., ; Katrich, E., Gorinstein, S. Human serum interactions with phenolic and aroma substances of Kaffir (Citrus hystrix) and Key lime (Citrus aurantifolia) juices. Journal of Luminescence, 201, 115-122 2018
Szterk, A., Zmyslowski, A., Gorinstein, S. Application of hydrophilic interaction liquid chromatography for the quantification of succinylcholine in Active Pharmaceutical Ingredient and medicinal product. Identification of new impurities of succinylcholine chloride. Heliyon, 412 2018,
Drzewiecki, J., Martinez-Ayala, AL, Lozano-Grande, MA., Leontowicz, H., Leontowicz, M., Jastrzebski, Z., Pasko, P., Gorinstein, S. In Vitro Screening of Bioactive Compounds in some Gluten-Free Plants. 2018, Applied Biochemistry and Biotechnology, 186, 847-860
Lozano-Grande, MA., Gorinstein, S., Espitia-Rangel, E., Davila-Ortiz, G., Martinez-Ayala, AL. Plant Sources, Extraction Methods, and Uses of Squalene. International Journal of Agronomy 2018
Pasko, P., Tyszka-Czochara, M., Galanty, A., Gdula-Argasinska, J., Zmudzki, P., Barton, H., Zagrodzki, P., Gorinstein, S. Comparative Study of Predominant Phytochemical Compounds and Proapoptotic Potential of Broccoli Sprouts and Florets. Plant Foods for Human Nutrition, 73, 95-100 2018
Pasko, P., Tyszka-Czochara, M., Namiesnik, J., Jastrzebski, Z., Leontowicz, H., Drzewiecki, J., Martinez-Ayala, AL., Nemirovski, A., Barasch, D., Gorinstein, S. Cytotoxic, antioxidant and binding properties of polyphenols from the selected gluten-free pseudocereals and their by-products: In vitro model. Journal of Cereal Science, 87, 325-333 2019
Park, HY., Shin, JH., Boo, HO., Gorinstein, S., Ahn, YG. Discrimination of Platycodon grandiflorum and Codonopsis lanceolata using gas chromatography-mass spectrometry-based metabolomics approach. Talanta, 192, 486-491 2019
Lubinska-Szczygel, M., Rozanska, A., Namiesnik, J., Dymerski, T., Szterk, A., Luksirikul, P., Vearasilp, S., Katrich, E., Gorinstein, S. Influence of steam cooking on pro-health properties of Small and Large variety of Momordica charantia. Food Control, 100, 335-349 2019

Hoffman, Amnon

Atsmon J., Cherniakov I., Izgelov D., Hoffman A., Domb A.J., Deutsch L., Deutsch F., Heffetz D. and Sacks H. PTL401, a new formulation based on pro-nano dispersion technology, improves oral cannabinoids bioavailability in healthy volunteers. J Pharm Sci. 107(5):1423-1429 2018
Bitton R., Tsuriel M., Suresh R., Breuer E., Reich R. and Hoffman A. Investigation of Intestinal Absorption Enhancers: Individual vs. Blends with the Carbamoylphosphonate JS403. J Bioequiv Availab 10:0-2 2018
Izgelov, D., Cherniakov, I., Aldouby Bier, G., Domb, A J; Hoffman, A. The effect of piperine pro-nano lipospheres on direct intestinal phase II metabolism: the raloxifene paradigm of enhanced oral bioavailability. Mol. Pharm. 15(4):1548-1555 2018
Dishon S, Shumacher A, Fanous J, Talhami A, Kassis I, Karussis D, Gilon C, Hoffman A and Nussbaum G Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88. Sci. Rep. 8(1):9476. 2018
Schumacher-Klinger, A; Fanous, J; Merzbach, S; Weinmueller, M; Reichart, F; Räder, A; Gitlin-Domaglaska, A; Gilon, C; Kessler, H; Hoffman, A. Enhancing oral bioavailability of cyclic RGD hexa-peptides by the Lipophilic Prodrug Charge Masking approach: Redirection of peptide intestinal permeability from paracellular to transcellular pathway. Mol. Pharm. 6;15(8):3468-3477 2018
Räder AFB, Weinmüller M, Reichart F, Schumacher-Klinger A, Merzbach S, Gilon C, Hoffman A, Kessler H. Orally Active Peptides: Is There a Magic Bullet? Angew Chem Int Ed Engl. 57(44):14414-14438. 2018
Shmoeli E., Izgelov D., Hoffman A. and Domb A.J. (2018) Pro-nanoliposphers (PNL) for improved oral bioavailability of insoluble drugs. Am. J Pharmacol Pharmacother DOI: 10.21767/2393-8862-C1-003
Dishon, S., Schumacher-Klinger, A., Gilon, C., Hoffman, A., and Nussbaum, G. Myristoylation confers oral bioavailability and improves the bioactivity of c(MyD 4-4), a cyclic peptide inhibitor of MyD88. Mol. Pharm. 164: 1516-1522 2019

Kohen, Ron

Kohen, Ron Activation of the Nrf2-Keap1 pathway in skin by unique activators: chemical, biological and environmental Free Radical Biology and Medicine Volume: 139 Issue: S1 Pages: S32-S32 Meeting Abstract: 100 Aug 1 2019

Lazarovici, Philip

Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, Ruppin E, Milyavsky M, Grossman R, Ram Z, Calderón M, Haag R, Satchi-Fainaro R. Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma. FASEB J. 32, 5835–5850. Oct 31 2018.
Haitao Wang, Philip Lazarovici and Wenhua Zheng. Forkhead Box Protein O. In: Encyclopedia of Signaling Molecules (S. Choi ed.). Springer International Publishing AG 2018.
Peng T, Jiang Y, Farhan M, Lazarovici P, Chen L, Zheng W. Anti-inflammatory Effects of Traditional Chinese Medicines on Preclinical in vivo Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug Discovery and Therapy. Front Pharmacol. Mar 7, 2019
Shilo D, Cohen G, Blumenfeld A, Goren K, Hanhan S, Sharon S, Haze A, Deutsch D, Lazarovici P. Tuftelin Is Required for NGF-Induced Differentiation of PC12 Cells. J Mol Neurosci.;68 (1):135-143. May 2019
Lazarovici P, Marcinkiewicz C, Lelkes PI. From Snake Venom's Disintegrins and C-Type Lectins to Anti-Platelet Drugs. Toxins (Basel). May 27, 2019;11(5).
Lazarovici P. Stem cells ageing. In :Encyclopedia of Gerontology and Population Aging. (Danan Gu and Matthew E. Dupre eds.) Springer Nature Switzerland AG 2019.

Levi-Schaffer, Francesca

Shamri, Revital; Dubois, Gerald; Erpenbeck, Veit J.; et al. Fevipiprant, a DP2 receptor antagonist, inhibits eosinophil migration towards mast cells Clinical and Experimental Allergy Volume: 49 Issue: 2 Pages: 255-257 FEB 2019
Karra, Laila; Gangwar, Roopesh Singh; Shamri, Revital; et al. Leukocyte CD300a Contributes to the Resolution of Murine Allergic Inflammation Journal of Immunology Volume: 201 Issue: 10 Pages: 2998-3005 NOV 15 2018
Levi-Schaffer, Francesca; Scheffel, Joerg Dangerous liaisons in anaphylaxis Science Volume: 362 Issue: 6415 Pages: 640-641 NOV 9 2018
Erlich, T. H.; Sharkia, I.; Landolina, N.; et al. Modulation of allergic responses by mitochondrial STAT3 inhibitors Allergy Volume: 73 Issue: 11 Pages: 2160-2171 NOV 2018
Barnig, Cindy; Bezema, Tjitske; Calder, Philip C.; et al. Activation of Resolution Pathways to Prevent and Fight Chronic Inflammation: Lessons From Asthma and Inflammatory Bowel Disease Frontiers in Immunology Volume: 10 Article Number: 1699 JUL 23 2019
Pahima, Hadas; Puzzovio, Pier Giorgio; Levi-Schaffer, Francesca 2B4 and CD48: A powerful couple of the immune system Clinical Immunology Volume: 204 Special Issue: SI Pages: 64-68 JUL 2019
Legrand, Fanny; Landolina, Nadine; Zaffran, Ilan; et al. Siglec-7 on peripheral blood eosinophils: Surface expression and function Allergy Volume: 74 Issue: 7 Pages: 1257-1265 JUL 2019
Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; et al. CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response Allergy Volume: 74 Issue: 7 Pages: 1377-1380 Published: JUL 2019
Levi-Schaffer, F. Inhibit activation or activate inhibition of mast cells and eosinophils: which weapon is better to fight allergic diseases? Inflammation Research Volume: 68 Supplement: 1 Pages: 21-21 2019
Karra, L.; Gangwar, R. S.; Puzzovio, P. G.; et al. Cd300a expression is modulated in atopic dermatitis and could influence the inflammatory repsonse Inflammation Research Volume: 68 Supplement: 1 Pages: 24-25 JUL 2019
Untersmayr, Eva; Bax, Heather J.; Bergmann, Christoph; et al. AllergoOncology: Microbiota in allergy and cancer-A European Academy for Allergy and Clinical Immunology position paper Allergy Volume: 74 Issue: 6 Pages: 1037-1051 JUN 2019
Sandham, D.; Shamri, R.; Erpenbeck, V; et al. Fevipiprant A Potent Selective Antagonist of The Prostaglandin D2 Receptor 2, Modulates The Allergic Effector Unit Via Inhibition Of Eosinophil Migration Towards Mast Cells Respirology Volume: 24 Special Issue: SI Supplement: 1 Pages: 105-105 Meeting Abstract: TP 007 MAR 2019
Roth-Walter, Franziska; Adcock, Ian M.; Benito-Villalvilla, Cristina; et al. Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper Allergy Volume: 74 Issue: 3 Pages: 432-448 MAR 2019
Puzzovio, Pier Giorgio; Karra, Laila; Gangwar, Roopesh Singh; et al. Leukocyte CD300a Contributes To The Resolution Of Murine Allergic Inflammation Journal of Allergy and Clinical Immunology Volume: 143 Issue: 2 Supplement: S Pages: AB186-AB186 Meeting Abstract: 567 FEB 2019

Matok, Ilan

Masarwa R, Levine H, Gorelik ES, Reif S, Perlman AS, Matok I. Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Cohort Studies. Am J Epidemiol. 187(8):1817-1827. (4.825; 14/176; 2). August 2018.
Perlman AS, Raccah BHS, Matok IPI*, Muszkat MPI*. Cognition and Dementia Related Adverse Effects with Sacubitril-Valsartan: Analysis of the FDA Adverse Event Report System Database. Journal of Cardiac Failure. 24(8):533-536. (3.765; 39/126). *Both authors directed the study and equally contributed to it. August 2018
Tsvirkun D, Ben-Nun Y, Merquiol E, Zlotver I, Meir K, Weiss Sadan T, Matok I, Popovtzer Rc, Blum G. CT Imaging of Enzymatic Activity in Cancer using Covalent Probes Reveal a Size-Dependent Pattern. J Am Chem Soc. 140(38):12010-12020. (14.357, 8/171). September 2018
Raccah BHS, Perlman AS, Zwas DRc, Hochberg-Klein Sc, Muszkat MPI, Matok IPI. Gender Differences in Efficacy and Safety of Direct Oral Anticoagulants in Atrial Fibrillation Systematic Review and Network Meta-Analysis. Ann Pharmacother. 52(11):1135-1142. (2.765; 112/261). November 2018
Raccah BHS, Rottenstreich, A, Zacks N, Muszkat M; Matok I, Perlman A, Kalish Y. Drug Interaction as a Predictor of Direct Oral Anticoagulants Drug levels in Atrial Fibrillation Patients. J Thromb Thrombolysis. 46(4):521-527. (2.62, 35/71; 34/65). November 2018
Masarwa R, Bar-Oz B, Gorelik E, Reif SC, Raccah B, Perlman A, Matok I. Prenatal Exposure to SSRIs and SNRIs and Risk for Persistent Pulmonary Hypertension of the Newborn: A Systematic Review, Meta-Analysis and Network Meta-Analysis. Am J Obstet Gynecol. 220(1):57. e1-57.e13. (5.732; 2/82). January 2019
Gorelik E, Masarwa R, Perlman A, Rothshild V, Abbassi M, Muszkat M, Matok I. Fluoroquinolones and Cardiovascular Risk: A Systematic Review, Meta-analysis and Network Meta-analysis. Drug Saf. 42(4):529-538. (3.585; 60/261; 30/180; 20/94) April 2019
Kabiri DPI, Masarwy RS, Schachter-Safrai Nc, Hirsh Raccah BS, Ezra Yc, Matok I ¬¬¬¬¬¬¬Trial of labor after caesarean delivery in twin gestations: Systematic review and meta-analysis. Am J Obstet Gynecol. ;220(4):336-347. (5.732; 2/82). April 2019
Rotshild VS, Azoulay L, Feldhamer I, Perlman AS, Glazer M, Muszkat M, Matok I. Calcium Channel Blockers Increase the Risk for Lung Cancer: A Population-Based Nested Case-Control Study. Ann Pharmacother. 53(5):445-452. (2.765; 112/261). May 2019.
Perlman A, Hochberg-Klein S, Choshen Cohen L, Dagan G, Hirsh-Raccah B, Horwitz E, Aldouby-Bier G, Negev T, Matok I, Azoulay L, Kalish Y, Muszkat M. Management strategies of the interaction between direct oral anticoagulant and drug-metabolizing enzyme inducers. J Thromb Thrombolysis. 47(4):590-595 (2.62, 35/71; 34/65). May 2019.
Raccah B, Rottenstreich, A, Zacks N, Matok I, Pollak A, Kalish Y. Appropriateness of Direct Oral Anticoagulant Dosing and its Relation to Drug Levels in Atrial Fibrillation Patients. J Thromb Thrombolysis. 47(4):550-557. (2.62, 35/71; 34/65). May 2019
Rotshild VS, Azoulay L, Feldhamer I, Perlman AS, Muszkat M, Matok I. Calcium Channel Blockers Use and the Risk for Prostate Cancer: A Population-Based Nested Case-Control Study. Ann Pharmacother. doi: 10.1177/1060028018814684. (2.765; 112/261). May 2019

Mechoulam, Raphael

Chiurchiù V., Leuti A., Smoum R., Mechoulam R., Maccarrone M.. Distinct ALIAmides directly modulate inflammatory responses of different subsets of primary human T lymphocytes. FASEB J. 32, 5716-5723 2018
Hen-Shoval D., Amar S., Shbiro L., Smoum R., Haj C., Mechoulam R., Zalsman G., Weller A., Shoval G.. Acute oral cannabidiolic acid methyl ester reduces depression-like behavior in two genetic animal models of depression. Behavioral Brain Research, 351, 1-3 2018
Shbiro L., Hen-Shoval D., Hazut N., Rapps K., Dar S., Zalsman G., Mechoulam R., Weller A., Shoval G.. Effects of cannabidiol in males and females in two different rat models of depression. Physiol. Behav. 201, 59-63 2018
Stark T., Ruda-Kucerova J., Iannotti A., D’Addario C., Di Marco R., Pekarik V., Drazanova E., Piscitelli F., Bari M., Babinska Z., Giurdanella G., Di Bartolomeo D., Salomone S., Sulcova A., Maccarrone M., Wotjak C.T, Starcuk ., Z., Drago F., Mechoulam R.,Di Marzo , Micale V. Peripubertal cannabidiol treatment rescued behavioral and neurochemical abnormalities in the MAM model of schizophrenia. Neuropharmacol.146, 212-221 2018
Feldman M., Smoum R., Mechoulam R., Steinberg D. Antimicrobial potential of endocannabinoid and endocannabinoid-like compounds against methicillin-resistant Staphylococcus aureus. Sci Rep. 8, 17696 2018
Baraghithy S., Smoum R., Drori A., Hadar R., Gammal A., Hirsch S., Attar-Namdar M., Nemirovski A., Gabet Y., Langer Y., Pollak Y., Schaaf C.P., Rech M.E., Gross-Tsur V., Bab I., Mechoulam R., Tam J.. Magel2 Modulates Bone Remodeling and Mass in Prader-Willi Syndrome by Affecting Oleoyl Serine Levels and Activity. J Bone Miner Res. 34, 93-105 2019
Donvito G., Piscitelli F., Muldoon P., Jackson A., Vitale R., D’Aniello E., Giordano C., Ignatowska-Jankowska B., Mustafa M., Guida F., Petrie G., Parker L., Smoum R., Sim-Selley L.J., Maione S., Lichtman A.H., Damaj M.I., Di Marzo V., Mechoulam R. N-Oleoyl glycine reduces nicotine reward and withdrawal in mice. Neuropharmacol. 148, 320-331 2019.
Linares IM, Zuardi A.W., Pereira LC, Queiroz RH, Mechoulam R, Guimarães FS, Crippa JA. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Rev Bras Psiquiatria. 41, 9-14 2019.
Magid L., Heymann S., Elgali M., Avram L., Cohen Y., Liraz-Zaltsman S., Mechoulam R., Shohami E. The receptor role of CB2 receptor in the recovery of mice after traumatic brain injury. J Neurotrauma. 36, 1836-1846 2019
Bar-Lev Schleider L, Mechoulam R., Saban N., Meiri G., Novak V. Real life experience of medical cannabis treatment in autism: analysis of safety and efficacy. Sci. Reports, 9, 200- 2019.

Moussaieff, Arieh

Shehadeh A, Bruck-Haimson R, Saidemberg D, Zacharia A, Herzberg S, Ben-Meir A, Moussaieff A. A shift in follicular fluid from triacylglycerols to membrane lipids is associated with positive pregnancy outcome. FASEB J. 2019 Jun

Priel, Avi

Maatuf Y, Geron M, Priel A. The Role of Toxins in the Pursuit for Novel Analgesics. Toxins (Basel). 2019 Feb 23;11(2). pii: E131. doi: 10.3390/toxins11020131.
Geron M, Kumar R, Zhou W, Faraldo-Gómez JD, Vásquez V, Priel A. TRPV1 pore turret dictates distinct DkTx and capsaicin gating. Proc Natl Acad Sci U S A. 11;115(50): 2018 Dec

Reich, Reuven

Onallah H, Davidson B, and Reich R Diverse effects of lysophosphatidic acid receptors on ovarian cancer signaling pathways Journal of Oncology, 2019
Sherman-Samis M, Onallah H, Holth A, Reich R, Davidson B. SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma. Gynecol Oncol. 153(3):651-660 2019 Jun
Onallah H, Catane LJ, Tropé CG, Hetland Falkenthal TE, Reich R, Davidson B. Activity and clinical relevance of autotaxin and lysophosphatidic acid pathways in high-grade serous carcinoma. Virchows Arch.;473(4):463-470. 2018 Oct Ringel, Israel
Shemesh, Asaf; Ginsburg, Avi; Levi-Kalisman, Yael; et al. Structure, Assembly, and Disassembly of Tubulin Single Rings BIOCHEMISTRY Volume: 57 Issue: 43 Pages: 6153-6165 Published: OCT 30 2018

Ringel, Israel

Shemesh, Asaf; Ginsburg, Avi; Levi-Kalisman, Yael; et al. Structure, Assembly, and Disassembly of Tubulin Single Rings BIOCHEMISTRY Volume: 57 Issue: 43 Pages: 6153-6165 Published: OCT 30 2018

Rubinstein, Abraham

Sharon-Gabbay R., Kenett R.S., Scaffaro R. and Rubinstein A. Synchronizing the release rates of salicylate and indomethacin from degradable chitosan hydrogel and its optimization by definitive screening design. Eur. J. Pharm. Sci., 125: 102-109, 2018.

Sasson, Shlomo

Sasson, Shlomo Roles of auto-regulated glucose transport, oxidative stress and lipid peroxidation at the bifurcation of protective and dysfunctional pathways in vascular endothelial cells
Gomes, Clarissa Pedrosa da Costa; Agg, Bence; Andova, Andrejaana; et al. Group Author(s): EU-CardioRNA Cost Action CA17129 Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129 NON-CODING RNA Volume: 5 Issue: 2 Article Number: 31 Published: JUN 2019
Xepapadaki, Eva; Maulucci, Giuseppe; Constantinou, Caterina; et al. Impact of apolipoprotein A1 or lecithin:cholesterol acyltransferase-deficiency on white adipose tissue metabolic activity and glucose homeostasis in mice BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE Volume: 1865 Issue: 6 Pages: 1351-1360 Published: JUN 1 2019
Uchida, Koji; Shibata, Takahiro; Toyokuni, Shinya; et al. Development of a novel monoclonal antibody against 4-hydroxy-2E,6Z-dodecadienal (4-HDDE)-protein adducts: Immunochemical application in quantitative and qualitative analyses of lipid peroxidation in vitro and ex vivo FREE RADICAL BIOLOGY AND MEDICINE Volume: 124 Pages: 12-20 AUG 20 2018
Sasson, Shlomo 4-Hydroxyalkenal-activated PPAR delta complexes mediate glucohormetic and lipohormetic interactions in diabetes FREE RADICAL BIOLOGY AND MEDICINE Volume: 124 Pages: 560-560 AUG 20 2018
Maulucci, Giuseppe; Di Giacinto, Flavio; De Angelis, Claudio; et al. Real time quantitative analysis of lipid storage and lipolysis pathways by confocal spectral imaging of intracellular micropolarity BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS Volume: 1863 Issue: 7 Pages: 783-793 JUL 2018

Shohami, Esther

Biegon A, Liraz-Zaltsman S, Shohami E. Stimulation of N-methyl-D-aspartate receptors by exogenous and endogenous ligands improves outcome of brain injury. Curr Opin Neurol. 31(6):687-692, 2018.
Magid, L., Heymann, S., Elgali, M., Avram, L., Cohen, Y., Liraz-Zaltsman, S., Mechoulam, R., Shohami, E. The role of CB2 receptor in the recovery of mice after traumaitc brain injury. J Neurotrauma 36(11):1836-1846. Epub 2019 Feb
Joy, M.T., Ben Assayag, E., Shabashov-Stone, D., Liraz-Zaltsman, S., Thareja, N.S., Arenas, M., Kliper, E., Korczyn, A.D., Kesner, E.L., Zhou, M. Huang, S., Silva, T.K., Katz, N., Bornstein, N.M., Silva, A.J., Shohami, E., Carmichael, S.T. CCR5 is a therapeutic target to stimulate recovery in stroke and traumatic brain injury. Cell;176(5):1143-1157, 2019.

Shurki, Avital

Amrani, Y. O. Rosenberg., A. Meshoulam, W. Said-Ahmad, C. Turich, N. Luu, T. Jacksier, A. Stankiewicz, S. Feinstein, A. Shurki, Sulfur isotopic composition of gas-phase organic sulfur compounds provides insights into the thermal maturation of organic-rich rocks" Geochim. Cosmochim. Acta, 259:91-108 2019

Tam, Yossi

Ganot N., Braitbard O., Gammal A., Tam J., Hochman J., Tshuva E.Y. In Vivo Anticancer Activity of a Non‐Toxic Inert Phenolato Ti Complex: High Efficacy on Solid Tumors Alone and Combined with Pt Drugs. ChemMedChem, 13:2290-2296. 2018
Zachut M., Kra G., Moallem U., Livshitz L., Levin Y., Udi S., Nemirovski A., Tam J. Characterization of the Endocannabinoid System in Subcutaneous Adipose Tissue in Periparturient Dairy Cows and its Association to Metabolic Profiles. PLoS One, 13:e0205996. 2018
Baraghithy S., Smoum R., Drori A., Hadar R., Gammal A., Hirsch S., Attar-Namdar M., Nemirovski A., Gabet Y., Langer Y., Pollak Y., Schaaf C.P., Rech M.E., Gross-Tsur V., Bab I., Mechoulam R., Tam J. Magel2 Modulates Bone Remodeling and Mass in Prader Willi Syndrome by Affecting Oleoyl Serine Levels and Activity. J Bone Miner Res, 34:93-105. 2019
Drori A., Permyakova A., Hadar R., Udi S., Nemirovski A., Tam J. (2019) Cannabinoid-1 Receptor Regulates Mitochondrial Dynamics and Function in Renal Proximal Tubular Cells. Diabetes Obes Metab, 21:146-159. Appeared on the January 2019 cover page of Diabetes Obes Metab
Azar S., Sherf-Dagan S., Nemirovski A., Webb M., Raziel A., Keidar A., Goitein D., Sakran N., Shibolet O., Tam J., Zelber-Sagi S. Circulating Endocannabinoids Are Reduced Following Bariatric Surgery and Associated with Improved Metabolic Homeostasis in Humans. Obes Surg, 29:268-276. 2019
Aran A., Eylon M., Harel M., Polianski L., Nemirovski A., Tepper S., Schnapp A., Cassuto H., Wattad N., Tam J. Lower Circulating Endocannabinoid Levels in Children with Autism Spectrum Disorder. Mol Autism, 10:2 2019
Abu-Remaileh M., Abu-Remaileh M., Akkawi R., Knani I., Udi S., Pacold ME., Tam J., Aqeilan R. WWOX somatic ablation in skeletal muscles alters glucose metabolism. Mol Metab, 22:132-140. 2019
Hinden L., Tam J. Do Endocannabinoids Regulate Glucose Reabsorption in the Kidney? Nephron 11:1-4. 2019
Hirsch S, Tam J (2019) Cannabis: From a Plant That Modulates Feeding Behaviors toward Developing Selective Inhibitors of the Peripheral Endocannabinoid System for the Treatment of Obesity and Metabolic Syndrome. Toxins, 11: 275.

Tirosh, Boaz

Meena NK, Pattanayak SP, Ben-Nun Y, Benhamron S, Kumar S, Merquiol E, Hövelmeyer N, Blum G, Tirosh B. mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity. Immunology. 155(4):505-518. 2018
Obiedat A, Seidel E, Mahameed M, Berhani O, Tsukerman P, Voutetakis K, Hatziioannou A, McMahon M, Avril T, Chevet E, Mandelboim O and Tirosh B. Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1. FASEB J. 33(3):3481-3495. 2019
Mahameed M, Obiedat A, Beck G, Johnson JC and Tirosh B. Low concentrations of cadmium chloride promote protein translation and improve cell line productivity. Biotechnol Bioeng. 116(3):569-580. 2019
Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy WS, Chintha C, Schubert T, Samali A, Chevet E, Eriksson LA, Huber M, Tirosh B. The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors. Cell Death Dis. 10(4):300. 2019
Weiss Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, Ben-Nun Y, Merquiol E, Tirosh B, Kessler B, Kaiser M, Blum G. Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation. Mol Cell Proteomics. 2019;18(7):1330-1344. 2019
Mahameed M, Sulieman A, Alkam D, Tirosh B. Towards Enhancing Therapeutic Glycoprotein Bioproduction: Interventions in the PI3K/AKT/mTOR Pathway. Cell Struct Funct.;44(2):75-83. 2019

Touitou, Elka

Natsheh H, Vettorato E, Touitou E. Ethosomes for dermal administration of natural molecules. Review. Curr Pharm Des. Epub ahead of print 2019.
Touitou E, Natsheh H, Duchi S. Buspirone nanovesicular nasal system for non-hormonal hot flushes treatment. Pharmaceutics. 2018, 10(3):82.
Natsheh H, Touitou E. Phospholipid Magnesome—a nasal vesicular carrier for delivery of drugs to brain. Drug Deliv Transl Res. 2018, 8(3): 806-819.

Tsvelikhovsky, Dmitry

Mostinski,Y., Lankri, D., Konovalov, Y., Nataf, R., Tsvelikhovsky, D. Proline-Promoted Dehydroxylation of a-Ketols. Chem. Sci. 2019, DOI: 10.1039/C9SC02543J.
Lankri, D., Haham, D., Lahiani, A., Lazarovici, P., Tsvelikhovsky, D Methylene-Cycloalkyacetate (MCA) Scaffold-Based Compounds as Novel Neurotropic Agents. ACS Chem. Neurosci. 2018, 9 (4), 691-698.

Weinstock, Marta

Zeeli S, Weill T, Finkin-Groner E, Bejar C, Melamed M, Furman S, Zhenin M, Nudelman A, Weinstock M. Synthesis and Biological Evaluation of Derivatives of Indoline as Highly Potent Antioxidant and Antiinflammatory Agents. J Med Chem 61: 4004-4019, 2018.
Shoham S, Linial M, Weinstock M. Age-induced spatial memory deficits in rats are correlated with specific brain region alterations in microglial morphology and gene expression. J Neuroimmune Pharmacology, 14: 251-262, 2019.
Dan R, Canetti L, Keadan T, Segman R, Weinstock M, Bonne O, Reuveni I, Goelman G. Sex differences during emotion processing are dependent on the menstrual cycle phase. Psychoneuroendocrinology 100: 85–95, 2019.
Schneider LS, Geffen Y, Rabinowitz J, Thomas RG, Schmidt R, Ropele S, Weinstock M. Low-dose ladostigil for mild cognitive impairment: a phase 2 placebo-controlled clinical trial. Neurology, 2019 in press.

Yavin, Eylon

Denichenko, P., Mogilevsky, M., Clery, A., Welte, T., Biran, J., Shimshon, O., Barnabas, G. D., Danan-Gotthold, M., Kumar, S., Yavin, E., Levanon, E. Y., Allain, F. H., Geiger, T., Levkowitz, G., and Karni, R. Specific inhibition of splicing factor activity by decoy RNA oligonucleotides, Nature communications 10. 2019
Hashoul, D., Shapira, R., Falchenko, M., Tepper, O., Paviov, V., Nissan, A., and Yavin, E. Red-emitting FIT-PNAs: "On site" detection of RNA biomarkers in fresh human cancer tissues, Biosensors & Bioelectronics 137, 271-278. 2019
Maximov, V. V., Akkawi, R., Khawaled, S., Salah, Z., Jaber, L., Barhoum, A., Or, O., Galasso, M., Kurek, K. C., Yavin, E., and Aqeilan, R. I. MiR-16-1-3p and miR-16-2-3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma, International journal of cancer. 2019
Mogilevsky, M., Shimshon, O., Kumar, S., Mogilevsky, A., Keshet, E., Yavin, E., Heyd, F., and Karni, R. Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment, Nucleic acids research 46, 11396-11404. 2018
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