Kidney development stops abruptly at the 35th week of gestation. Despite multiple kidney injuries throughout life, he kidney lacks regeneration ability of new nephrons. Patients with a history of prematurity have a significantly higher risk of chronic kidney disease in adulthood secondary to low nephron number.
We aim to understand the changes which take place as a result of preterm birth which leads to a low nephron number to find ways to reduce the risk of chronic kidney disease in this population.