1. The mechanisms of skeletal fragility and sarcopenia in Diabetes. We use cell line models, primary cultures and mouse models to understand why patients with diabetes have deterioration in bone and muscle health. We use transcriptomics and proteomics to identify novel therapeutic targets,. Studies in patients with diabetes are also included. This project received a BIRAX grant.
Frontiers in Physyology, 2022, 13:812157
2. Beyond estrogens: we look for new therapeutic targets to aleviate cardiometabolic dysfunction that accompanies the menopausal transition. We use animal model of human menopause and studies in women identifying novel biomarkers and therapeutic targets. This project was awarded a 5 year ISF grant in 2021
Molecular metabolism, 2022, June; 60:101482
Please email to: rivkap@mail.huji.ac.il or rivkap@hadassah.org.il