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Brain Disease Research Center
Brain Disease Research Center
עברית

2023 Doris Cecelia Levy Memorial Seminar on Brain Disease

​Keynote speakers

Ashley Bush

University of Melbourne, Australia

Oscar Marín

King's College London, UK

Stephanie Cragg

University of Oxford, UK

​Speakers

Gali Umschweif

The Hebrew University of Jerusalem

Anat Kahan

The Hebrew University of Jerusalem

Omer Revah

The Hebrew University of Jerusalem 

Chaim Putterman

Bar-Ilan University

Haitham Amal

The Hebrew University of Jerusalem

Raz Yirmiya

The Hebrew University of Jerusalem

Asaf Marco

The Hebrew University of Jerusalem

Avi Ashkenazi

Tel Aviv University

Simone Engelender

Technion

Zeev Melamed

The Hebrew University of Jerusalem

Inna Slutsky

Tel Aviv University

Shira Knafo

Ben-Gurion University

​Scientific committee:

Ayal Ben-Zvi, Josh Goldberg, Amit Lotan, Gali Umschweif-Nevo
​Free registration

Scientific Program

Day One – Tuesday, 12 September

13:00 – 14:00
 Registration
14:00 – 14:30 Introduction and greetings
14:30 – 15:30
Plenary 1.
Chair: Dr. Amit Lotan
14:30-15:15 Prof. Ashley Bush, Florey Institute of Neuroscience & Mental Health, University of Melbourne, Australia
Brain iron and ferroptosis in neuropsychiatric disorders
15:15-15:30 Q&A
15:30 – 16:00 Coffee break
16:00 – 18:00
Regular Session 1: Neuropsychiatric disorders
Chair: Prof. Ronen Segman
16:00 Speaker 1 (16:24 Q&A) Gali Umschweif
Neurensin-2 a novel cell-type-specific drug target to treat depression and anxiety
16:30 Speaker 2 (16:54 Q&A) Shira Knafo, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Interplay Between Hippocampal TACR3 and Systemic Testosterone in Regulating Anxiety-Associated Synaptic Plasticity
17:00 Speaker 3 (17:24 Q&A) Raz Yirmiya, Department of Psychology, the Hebrew University of Jerusalem, Israel
A personalized medical approach to depression based on restoration of microglia homeostasis
17:30 Speaker 4 (17:54 Q&A) Anat Kahan, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot, Israel
Dysregulated mammalian estrus cycle rescued by timed activation of VIP neurons in the circadian pacemaker and late afternoon light exposure

Day Two – Wednesday, 13 September

09:00 – 09:30 Coffee, Registration
09:30 – 10:30
Plenary 2.
Chair: Dr. Gali Umschweif
9:30-10:15 Prof. Oscar Marín, Centre for Developmental Neurobiology, University College London, United Kingdom
Cortical interneurons in health and disease
10:15-05:30 Q&A
10:30 – 11:00 Coffee Break
11:00 – 13:00
Regular Session 2: Neurodevelopmental/Neuroimmune disorders
Chair: Prof. Tamir Ben-Hur
11:00 Speaker 5 (11:24 Q&A) Omer Revah, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot, Israel
Using stem cells to build a model of the human cortex in vivo
11:30 Speaker 6 (11:54 Q&A) Haitham Amal, Institute of Drug Research, The Faculty of Medicine, The Hebrew University of Jerusalem, Israel
The NO Answer for Autism Spectrum Disorder
12:20 Speaker 7 (12:24 Q&A) Asaf Marco, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot, Israel
DNA methylation dysregulation of non-coding regions in individuals with Williams syndrome is associated with myelination deficits and cortical development
12:30 Speaker 8 (12:54 Q&A) Chaim Putterman, Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel
The key role of the choroid plexus in the pathogenesis of neuropsychiatric lupus
13:00 – 14:30 Lunch
14:30 – 15:15
Plenary 3.
Chair: Prof. Josh Goldberg
Prof. Stephanie Cragg, Centre for Cellular and Molecular Neurobiology, University of Oxford, United Kingdom
Gating dopamine transmission in health and disease
15:15-15:30 Q&A
15:30 – 16:00 Coffee break
16:00 – 18:00
Regular Session 3: Neurodegenerative disorders
Chair: Prof. Ronit Sharon
16:00 Speaker 5 (16:24 Q&A) Avi Ashkenazi Sackler Faculty of Medicine, Tel Aviv University
Mechanisms of autophagy and the ubiquitin-proteasome pathways and relevance to trinucleotide repeat disorders
16:30 Speaker 6 (16:54 Q&A) Simone Engelender, Faculty of Medicine, Technion, Haifa, Israel
Expanding the frontiers: Investigating protein aggregation beyond α-synuclein in Parkinson's disease
17:00 Speaker 7 (17:24 Q&A) Zeev Melamed, Institute of Medical Research Israel Canada, The Faculty of Medicine, The Hebrew University of Jerusalem
Targeting impaired RNA metabolism in age-dependent neurodegeneration
17:30 Speaker 8 (17:54 Q&A) Inna Slutsky, Sackler Faculty of Medicine, Tel Aviv University
Neural Basis of a Silent Alzheimer’s Disease Phase
18:00 Concluding Remarks
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