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Research Interests

During metazoan development, a small number of signaling pathways are iteratively used to orchestrate diverse processes such as cell fate determination, apoptosis, cell proliferation, and cell migration. The coordinated temporal and spatial regulation of these pathways underlies the final cellular makeup, size, and shape of organs and dysregulation of these pathways can lead to human diseases.

We take advantage of the powerful genetic and molecular techniques (including genome engineering) available in Drosophila, which facilitate both gene discovery and in vivo analysis of gene function, to study developmental, cellular and molecular mechanisms involved in organ formation.