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​Research Interests

Using mouse models of cancer to identify cancer cell vulnerabilities and target them for therapy

  • Deciphering the gut microbiome regulation of p53 mutations in intestinal cancer development
  • Studying the mechanisms that promotes primary epithelial invasion to initiate cancer
  • Developing small molecule multi-kinase inhibitors as novel anti-leukemia agents
  • Exploring the potential of the multi-kinase inhibitors in Melanoma and Colorectal Cancer treatment
  • Evaluating the therapeutic potential of small molecule inhibitors which glue CKIα to ubiquitin ligase cereblon for protein degradation