Our Goal

We have established, and are further developing, state-of the art, leading tools for the structure-based computational manipulation of proteins and their interactions. In the long term, we will bring those techniques to a point where we can (1) reliably apply them to large scale data and address general questions at the level of system biology; (2) consolidate routine applications for a range of interesting specific biomedical and biotechnological systems. Towards this goal, we have established, and continue to establish fruitful collaborations with experimental groups, which allow the cycling between modeling and experiment that is critical for our advancement in both our understanding of the basic underlying principles of protein intera