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Selected Publications


Single cell RNA-seq reveals developmental plasticity with coexisting oncogenic and immune evasion programs in ETP-ALLAnand P*, Guillaumet-Adkins A*, Dimitrova V*, Yun H*, Drier Y*, Sotudeh N, Rogers AJ, Ouseph MM, Nair M, Potdar S, Isenhart R, Kloeber JA, Vijaykumar T, Niu L, Vincent TL, Guo G, Frede J, Harris M, Place A, Silverman LB, Teachey DT, Lane AA, DeAngelo DJ, Aster JC, Bernstein B, Lohr J#, Knoechel B#. Blood 2021.

Large-scale implementation of pooled RN​A-extraction and RT-PCR for SARS-CoV-2 detection. Ben-Ami R*, Klochendler A*, Seidel M*, Sido T, Gurel-Gurevich O, Yassour M, Meshorer E, Benedek G, Fogel I, Oiknine-Djian E, Gertler A, Rotstein Z, Lavi B, Dor Y#, Wolf DG#, Salton M#, Drier Y#, on behalf of The Hebrew University-Hadassah COVID-19 diagnosis team. Clinical Microbiology and Infection, 2020. 

Enhancer and super-enhancer regulation and its disruption in cancer. Drier Y. Current Opinion in Systems Biology, 2020.

Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs. Flavahan WA*, Drier Y*#, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD#, Bernstein BE#. Nature, 2019.

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Cejas P*, Drier Y*#, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE#, Shivdasani RA#. Nature Medicine, 2019.

Insulator dysfunction and oncogene activation in IDH mutant gliomas. Flavahan WA*, Drier Y*, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE#. Nature, 2016.

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. Drier Y, Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L, Qi J, Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster JC, Knoechel B#, Bernstein BE#. Nature Genetics, 2016.

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma. Ryan RJ*, Drier Y*, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE#. Cancer Discovery, 2015.

Pathway-based personalized analysis of cancer. Drier Y, Sheffer M, Domany E#. PNAS, 2013.

Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. Drier Y, Lawrence MS, Carter SL, Stewart C, Gabriel SB, Lander ES, Meyerson M, Beroukhim R, Getz G#. Genome Research, 2013.

The genomic complexity of primary human prostate cancer. Berger MF*, Lawrence MS*, Demichelis F*, Drier Y*, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, Fennell T, Parkin M, Saksena G, Voet D, Ramos AH, Pugh TJ, Wilkinson J, Fisher S, Winckler W, Mahan S, Ardlie K, Baldwin J, Simons JW, Kitabayashi N, MacDonald TY, Kantoff PW, Chin L, Gabriel SB, Gerstein MB, Golub TR, Meyerson M, Tewari A, Lander ES, Getz G, Rubin MA#, Garraway LA#. Nature, 2011.


* Co-first authors

# Corresponding author


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