Sign In



Wu MR*, Nissim L*, Stupp D, Pery E, Binder-Nissim A, Weisinger K, Enghuus C, Palacios SR, Humphrey M, Zhang ZZ, Novoa EM, Kellis M, Weiss R, Rabkin SD, Tabach Y, Lu TK. A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS). Nature Communications (2019)

Nissim, L.*, Wu, M.R.*, Pery, E., Binder-Nissim, A., Suzuki, H.I., Stupp, D., Wehrspaun, C., Tabach, Y., Sharp, P.A., and Lu, T.K. Synthetic RNA-based immunomodulatory gene circuits for cancer immunotherapy. Cell (2017)
Lee, G., Atia, L., Lan, B., Sharma, Y., Nissim, L., Wu, M.R., Pery, E., Lu, T.K., Park, C.Y., Butler, J.P., et al. Contact guidance and collective migration in the advancing epithelial monolayer. Connect Tissue Res (2017)
Morel, M., Shtrahman, R., Rotter, V., Nissim, L.**, and Bar-Ziv, R.H**. Cellular heterogeneity mediates inherent sensitivity-specificity tradeoff in cancer targeting by synthetic circuits. Proc Natl Acad Sci USA (2016)
Nissim, L.*, Perli, S.D.*, Fridkin, A., Perez-Pinera, P., and Lu, T.K. Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Molecular Cell (2014)
Jusiak, B., Daniel, R., Farzadfard, F., Nissim, L., Purcell, O., Rubens , J., and Lu, T.K. Synthetic Gene Circuits. Encyclopedia of Molecular Cell Biology and Molecular Medicine (2014)
Nissim, L., and Bar-Ziv, R.H. A tunable dual-promoter integrator for targeting of cancer cells. Molecular systems biology (2010)
Nissim, L., Beatus, T., and Bar-Ziv, R. An autonomous system for identifying and governing a cell's state in yeast. Physical biology (2007)
Matas, D., Milyavsky, M., Shats, I., Nissim, L., Goldfinger, N., and Rotter, V. p53 is a regulator of macrophage differentiation. Cell death and differentiation  (2004)
Peller, S., Frenkel, J., Lapidot, T., Kahn, J., Rahimi-Levene, N., Yona, R., Nissim, L., Goldfinger, N., Sherman, D.J., and Rotter, V. The onset of p53-dependent apoptosis plays a role in terminal differentiation of human normoblasts. Oncogene (2003)